Steps:
1) Install Salix
2) Change hinting to slight (just to make the display standout)
2) Install Calibre
3) Font display in Calibre is the same as in the rest of Salix
4) Update Salix
5) Font display in Calibre resembles full or medium hinting (but not quite

6) Change hinting from slight to anything not slight and back to slight
7) Font display in calibre now displays correctly (until I reboot)
It first showed itself immediately after an upgrade from calibre .40 -> .41 (this was a two or three months ago), and is absolutely confined to Salix 13.37 (XFCE, I have not installed any other DE), it doesn't not show itself in any other distro I've tried (LM, Fedora(XFCE or GNOME Shell), Ubuntu, Xubuntu, LMDE-XFCE or SolusOS).
I am assuming that it is a Calibre problem (as fonts in the rest of Salix display as set), but I'm hoping someone can give me a hint as to why
